Faculty Projects and Publications

Andre P. Seale

Assistant Research Faculty

Education

Research Interests

  1. Osmoreception: signal transduction of environmental salinity changes into physiological responses at the cellular and organismic levels in fish; regulation of prolactin cells by external and neuroendocrine factors and the role of second messenger systems.
  2. Osmoregulation: salt and water balance and its interplay with growth, metabolism and stress in fish.
  3. Environmental adaptation of fish: endocrine and specialized cellular responses to extreme conditions.

Publications

PEER-REVIEWED PUBLICATIONS

Yamaguchi, Y., Takagi, W., Kuraku, S., Moriyama, S., Bell, J. D., Seale, A. P., Lerner, D. T., Grau, E. G., Hyodo, S. (2015). Discovery of conventional prolactin from the holocephalan elephant fish, Callorhinchus milii. Gen. Comp. Physiol. In press.

Inokuchi, M., Breves, J., Moriyama, S., Watanabe, S., Kaneko, T., Lerner, D. T., Grau, E. G., Seale, A. P. (2015). Prolactin 177, prolactin 188 and extracellular osmolality independently regulate the expression of ion transport effectors in the gills of Mozambique tilapia. Am. J. Physiol. In press.

Nakamura, M., Nozu, R., Ijiri, S., Kobayashi, T., Yamaguchi, Y., Seale, A. P., Lerner, D.T., Grau, E. G. (2015). Sexual characteristics of high-temperature sterilized male Mozambique tilapia, Oreochromis mossambicus. Zool. Lett. 1-21.

Furukawa, F., Watanabe, S., Seale, A. P., Breves, J. P., Lerner, D. T., Grau, E. G., Kaneko, T. (2015). In vivo and in vitro studies reveal that branchial expression of ROMKa in seawater-acclimated Mozambique tilapia directly responds to high-K+ stress. Comp. Biochem. Physiol. 187, 111-118.

Moorman, B. P., Lerner, D. T., Grau, E. G., Seale, A. P. (2015). The effects of acute salinity challenges on Osmoregulation in Mozambique tilapia reared in a tidally changing salinity. J. Exp. Biol. 218, 731-9.

Zikos, A., Seale, A. P., Lerner, D. T., Grau, E. G., Korsmeyer, K. E. (2014). Effects of salinity on metabolic rate and branchial expression of genes involved in metabolism and mitochondrial biogenesis in Mozambique Tilapia (Oreochromis mossambicus). Comp. Biochem. Physiol. 178, 121-31.

Seale, A. P., Stagg, J. J., Yamaguchi, Y., Breves, J. P., Soma, S., Watanabe, S., Kaneko, T., Cnaani, A., Harpaz, S., Lerner, D. T., Grau, E.G. (2014). Effects of salinity and prolactin on the transcription of ion transporters, ion pumps and prolactin receptors in Mozambique tilapia intestine. Gen. Comp. Endocrinol. 206, 146-54.

Seale, L. A., Gilman, C. L., Moorman, B. P., Berry, M. J., Grau, E.G., Seale, A. P. (2014). Effects of acclimation salinity on the expression of selenoproteins in the tilapia, Oreochromis mossambicus. J. Tr. El. Med. Biol. 28(3), 284-92.

Douros, J. D., Baltzegar, D. A., Breves, J. P., Lerner, D. T., Seale, A. P., Grau, E. G., Borski, R. J. (2014) Prolactin is a major inhibitor of hepatic Leptin A synthesis and secretion: studies utilizing a homologous Leptin A ELISA in the tilapia. Gen. Comp. Endocrinol. 207, 86-93.

Breves, J. P., Tipsmark, C. K., Stough, B. A., Seale, A. P., Flack, B. R., Moorman, B. P., Lerner, D. T., Gau, E. G. (2014) Nutritional status and growth hormone regulate insulin-like growth factor binding protein (IGFBP) transcripts in Mozambique tilapia. Gen. Comp. Endocrinol. 207, 66-73.

Moorman, B. P., Inokuchi, M., Yamaguchi, Y., Lerner, D. T., Grau, E. G., Seale, A. P. (2014). The osmoregulatory effects of rearing Mozambique tilapia in a tidally changing salinity. Gen. Comp. Endocrinol. 207, 94-102.

Breves J. P., Seale, A. P., Moorman, B. P., Lerner, D. T., Moriyama, S., Hopkins, K. D., Grau, E.G. (2014). Pituitary control of branchial NCC, NKCC and Na+, K+-ATPase α-subunit gene expression in Nile tilapia, Oreochromis niloticus. J. Comp. Physiol. 184, 513-523.

Seale, A. P., Yamaguchi, Y., Johnstone III, W.M., Borski, R.J., Lerner, D.T. Grau, E.G. (2013). Endocrine regulation of prolactin cell function and modulation of osmoreception in the Mozambique tilapia. Gen. Comp. Endocrinol. 192, 191-203.

Rowell, T.R., Seale, L. A., Seale, A. P., Banuelos, G. S., Grau, E. G., Riley, L.G. (2013). Effects of selenium-enriched meal on growth performance, endocrine control of growth and selenoprotein expression in tilapia (Oreochromis mossambicus). Integr. Comp. Biol. 53, E185-E185.

Seale, A. P., Watanabe, S., Breves, J. P, Lerner D.T., Grau, E.G. (2012). Differential regulation of TRPV4 by acclimation salinity and extracellular osmolality in euryhaline tilapia. Gen Comp. Endocrinol. 178, 123-130.

Seale, A. P., and Watanabe, S., Grau, E. G. (2012). Osmoreception: perspectives on signal transduction and environmental modulation. Gen. Comp. Endocrinol. 176, 354-360.

Seale, A. P., Moorman B. P., Stagg, J. J., Breves, J. P., Lerner, D. T., Grau, E.G. (2012). Prolactin 177, prolactin 188 and prolactin receptor 2 in the pituitary of the euryhaline tilapia, Oreochromis mossambicus, are differentially osmosensitive. J. Endocrinol . 213, 89-98.

Watanabe, S., Seale, A. P., Grau, E.G, Kaneko, T. (2012). TRPV4 stretch-activated cation channel mediates hyposmolality-induced prolactin release from prolactin-producing cells of Mozambique tilapia, Oreochromis mossambicus. Am. J. Physiol. 302, R1004-1011.

Tipsmark, C. K., Breves, J. P., Seale, A. P., Lerner, D. T., Hirano, T., Grau, E. G. (2011). Switching of Na+, K+-ATPase isoform gene expression by salinity and prolactin in the gill of a euryhaline cichlid. J. Endocrinol. 209, 237-44.

Breves, J. P., Seale, A. P., Helms, R. E., Tipsmark, C. K., Hirano, T., Grau, E. G, (2011). Dynamic gene expression of GH/PRL-family hormone receptors in gill and kidney during freshwater-acclimation of Mozambique tilapia. Comp. Biochem. Physiol. A Mol. Integr. Physiol.. 158, 194-200.

Seale, A. P., Mita, M., Hirano, T., and Grau, E. G. (2011). Involvement of the cAMP messenger system and extracellular Ca2+ during hyposmotically-induced prolactin release in the Mozambique tilapia. Gen. Comp. Endocrinol. 170, 401-407.

Seale, A. P., de Jesus, L. A., Park, M. C., and Kim, Y. S. (2006). Vanadium and insulin increase adiponectin production in 3T3-L1 adipocytes. Pharmacol. Res. 54:30-8.

Seale, A. P., Fiess, J. C., Hirano, T., Cooke, I. M., and Grau, E. G. (2006). Disparate release of prolactin and growth hormone from the tilapia pituitary in response to osmotic stimulation. Gen. Comp. Endocrinol. 145, 222-31.

Kajimura, S., Seale, A. P., Hirano, T., and Grau, E. G. (2006). Ouabain as a possible osmoregulatory hormone. J. Exp. Zool. 305, 138-138.

Seale, A. P., Hirano, T., and Grau, E. G. (2006). Osmoreception: a fish model for a fundamental sensory modality. In "Fish Endocrinology" (G. Zaccone and M. Reinecke, Eds.). pp. 419-440 Oxford & IBH Publishing Company.

Kajimura, S., Seale, A. P., Hirano, T., and Grau, E. G. (2005). Physiological Concentrations of Ouabain Rapidly Inhibit Prolactin Release from the Tilapia Pituitary. Gen. Comp. Endocrinol. 143, 240-50.

Shepherd, B. S., Weber, G. M., Vijayan, M. M., Seale, A. P., Riley, L. G., Richman, N. H., Hirano, T., and Grau, E. G. (2005). Control of growth in tilapia: developments and prospects. In "Tilapias: Culture, Nutrition and Feeding" (C. D. Webster and C. E. Lim, Eds.). Haworth Press.

Seale, A. P., de Jesus, L. A., Kim, S. Y., Choi, Y. H., Lim, H. B., Hwang, C. S., and Kim, Y. S. (2005). Development of an automated protein-tyrosine phosphatase 1B inhibition assay and the screening of putative insulin-enhancing vanadium (IV) and zinc (II) complexes. Biotechnol. Lett. 27, 221-5.

Seale, A. P., Hirano, T., and Grau, E. G. (2005). Stimulus-secretion coupling in the osmoreceptive prolactin cell of the tilapia. In "Mechanosensitivity of the Cells from Various Tissues" (A. Kamkin and I. Kiseleva, Eds.), pp. 371-389. Academia, Moscow.

Seale, A. P., Weber, G. M., Richman, N. H., 3rd, Stetson, M., Hirano, T., and Grau, E. G. (2004). Cell size regulates hormone release in the osmoreceptive prolactin cell of the euryhaline tilapia, Oreochromis mossambicus. In "Trends in Comparative Endocrinology. Proceedings of the Fifth Congress of Asia and Oceania Society for Comparative Endocrinology" (T. Oishi, K.Tsutsui, S. Tanaka, and S. Kikuyama, Eds.), pp. 138-140.

Seale, A. P., Cooke, I., Hirano, T., and Grau, G. (2004). Evidence that IP(3) and Ryanodine-sensitive Intra-cellular Ca Stores are not Involved in Acute Hyposmotically-Induced Prolactin Release in Tilapia. Cell. Physiol. Biochem. 14, 155-66.

Weber, G. M., Seale, A. P., Richman, N. H., Stetson, M., and Grau, E. G. (2004). Hormone release is tied to changes in cell size in the osmoreceptive prolactin cell of a euryhaline teleost fish, the tilapia, Oreochromis mossambicus. Gen. Comp. Endocrinol. 138, 8-13

OTHER PUBLICATIONS

Seale, A.P. and Seale, L.A. (2009). “Tropical Marine Gardens” 240 pps. Metalivros, São Paulo. ISBN 978-85-85371-83-8

Pinca S., Koltes K.,  Seale A. P. (2006). Ailuk Marine Resources Assessment, 2006.

 

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